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Chemical Name:O-Phthalaldehyde

CAS No.:643-79-8

Molecular Formula:C8H6O2

Molecular Weight:134.13

Appearance:Yellow or light yellow crystalline

Sample:Free samples are available

Capacity: 200 MT per year

Structural formula:

Product Description

Typical Properties

Item Specifications
Appearance Yellow or light yellow crystalline
Water ≤0.05%
Melting 54-56°C
Assay ≥99.0% (GC)

Core Product Advantages

Excellent Disinfection Performance
Broad-spectrum and highly efficient, rapidly kills bacteria, viruses, fungi, and spores. Features low irritation, minimal odor, and significantly lower corrosivity compared to glutaraldehyde, causing minimal damage to precision instruments like endoscopes.
High Detection Sensitivity
Reacts rapidly with primary amines to generate strong fluorescence, enabling trace-level detection at the pmol scale with a fast reaction rate.
Strong Chemical Reactivity
Its dialdehyde structure easily undergoes condensation and addition reactions, making it highly suitable for organic synthesis and the synthesis of pharmaceutical intermediates.
Good Compatibility
Can be compounded with surfactants and buffer systems, making it adaptable for medical disinfection and analytical reagent formulations.

Main Application

1. Medical Disinfection (Core Application)
  • 2% Ortho-phthalaldehyde (OPA) Disinfectant: Used for high-level disinfection and sterilization of flexible endoscopes and medical instruments in hospitals.
  • Applicable for the disinfection of dental instruments, dialysis equipment, and laparoscopic instruments.
  • Free from the pungent odor of glutaraldehyde, offering better tolerance for medical staff.
2. Chemical Analysis and Detection Reagents
  • Pre-column derivatization fluorescent reagent for amino acids and peptides, used in HPLC (High-Performance Liquid Chromatography) detection.
  • Fluorescent quantitative detection of primary amines, alkaloids, and protein thiol groups, widely used in biochemical, food, and environmental testing.
  • Raw material for OPA test solution specified in pharmacopoeias.
3. Pharmaceutical and Organic Synthesis Intermediates
  • Synthesis of antiplatelet drugs, antibiotics, cardiovascular drugs, and fluorescent probes.
  • Used in the synthesis of heterocyclic compounds and fine organic chemicals.
4. Other Fields
  • Dyes, fluorescent materials, polymer crosslinking agents, biological labeling reagents, etc.

Package & Storage

Packaging

25kg/drum

Storage Conditions

Keep in a well-closed, light-resistant, dry and cool place.

Frequently Asked Questions (FAQ)

Q1: What is the purity (assay) level of Ortho-phthalaldehyde (OPA)?
The product features a high assay specification of ≥99.0% as determined by Gas Chromatography (GC).
Q2: Why is OPA preferred over glutaraldehyde for medical disinfection?
OPA offers lower irritation, minimal odor, and significantly reduced corrosivity compared to glutaraldehyde, ensuring better tolerance for medical staff and minimal damage to sensitive instruments like endoscopes.
Q3: What are the primary applications of OPA in chemical analysis?
It serves as a pre-column derivatization fluorescent reagent for HPLC detection of amino acids/peptides and is used for fluorescent quantitative detection of primary amines, alkaloids, and protein thiol groups.
Q4: What pharmaceuticals can be synthesized using OPA as an intermediate?
OPA is used in the organic synthesis of antiplatelet drugs, antibiotics, cardiovascular drugs, fluorescent probes, and various heterocyclic compounds.
Q5: How should Ortho-phthalaldehyde be properly stored?
It should be stored in a well-closed container that is kept light-resistant, dry, and in a cool environment to maintain product stability.
Q6: What is the standard packaging size for this product?
The standard packaging is 25kg per drum.

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