China Azelaic Acid CAS 123-99-9 Suppliers, Product

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China Azelaic Acid CAS 123-99-9 Suppliers, Product

Chemical Name: Azelaic acid
CAS No.: 123-99-9
Molecular Formula: C9H16O4
Molecular Structure:

Molecular Weight:188.22
Appearance:Crystalline powder
Sample:Free samples are available

Key Properties: Melting point approx. 106°C; Boiling point 286°C (at 100 mmHg). Slightly soluble in cold water (approx. 2.4 g/L at 20°C); freely soluble in hot water, ethanol, propylene glycol, and ethyl acetate. Chemically stable and resistant to oxidation and decomposition. Exhibits typical reactions of dibasic carboxylic acids (salt formation, esterification).

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Product Description

Typical Properties

Item	Specifications
Appearance	Crystalline powder
Moisture	≤0.2%
Assay	≥98%
Acid value	585-610
Melting point	105-110℃
particle size	≥60 mesh
Plumbum	≤1 ppm
Arsenic	≤1 ppm
chromium	≤1 ppm
Color	≥ 95%
Color	≥ 99%

Application

1. Dermatology / Skincare

Acne Treatment

Inhibits Cutibacterium acnes (formerly P. acnes), regulates follicular keratinization, and exerts anti-inflammatory effects. Common formulations include 15% gel and 20% cream; recommended for topical use by the Chinese Guidelines for Acne Treatment.

Whitening & Mark Fading

Selectively inhibits tyrosinase in abnormal melanocytes to fade acne marks, post-inflammatory hyperpigmentation (PIH), and melasma. Its irritation potential is significantly lower than that of tretinoin or high-concentration AHAs.

Oil Control & Soothing

Inhibits 5α-reductase to reduce sebum secretion. Suitable for oily, acne-prone skin and as adjunctive care for rosacea.

Common Dosage Forms

Gels, creams, moisturizers, serums, and masks.

10%: Daily skincare (suitable for sensitive skin)
15%: Mainstay for acne treatment
20%: Pharmaceutical grade (requires tolerance building)

2. Industrial Chemical Sector

Plasticizers: Synthesis of Dioctyl Azelate (DOZ), Diisooctyl Azelate, etc. Used in PVC and rubber, offering excellent heat resistance, cold resistance, and electrical insulation properties; suitable for products in low-temperature environments.
Lubricants / Synthetic Oils: Used as components for precision instruments and aviation hydraulic fluids.
Coatings / Resins: Modified polyesters and alkyd resins to improve coating flexibility and weatherability.

3. Other Applications

Feed additives, electroplating brighteners, polymer crosslinking agents, etc.

Application Areas

1. Hair Care Industry (Core Application)

Cold Wave Lotions / Perm Solutions: Softens hair keratin and reshapes disulfide bonds to achieve permanent curling; serves as the core reducing agent in cold perms.
Hair Straightening Creams / Relaxers: Cleaves disulfide bonds to soften hair, working in conjunction with neutralizers to achieve permanent straightening.
Depilatory Creams / Lotions: Softens body hair keratin to facilitate easy removal; the preferred choice for mild depilatory products.
Recommended Concentration: 5%–15% for perming/straightening; 2%–8% for depilatory use.

2. Industrial & Other Fields

Metal Corrosion Inhibition: Forms a protective FeS film in high-temperature brine/completion fluids to inhibit carbon steel corrosion (140–200℃).
Chemical Analysis: Used as a masking agent and reducing agent for the photometric determination of ions such as iron, aluminum, silver, and tin.
Material Modification: Serves as a thiolating agent for the preparation of adsorption materials and functional polymers.
Electronic Cleaning: Acts as an auxiliary agent for metal surface treatment and cleaning.

Package

25kg fiber drums / paper bags (lined with PE bag)

Storage

Store in a well-ventilated, cool, and dry place; keep separate from oxidizing agents.

Frequently Asked Questions (FAQ)

What is the purity assay and physical appearance of this product?

The product is supplied as a high-purity crystalline powder with an assay of ≥98% and moisture content controlled at ≤0.2%.

What concentration is recommended for dermatology and skincare applications?

For daily skincare and sensitive skin, 10% is recommended; 15% is the mainstay concentration for acne treatments, while 20% is typically used in pharmaceutical-grade formulations.

How is the material used in industrial hair care solutions?

It serves as a core reducing agent in cold wave lotions, hair straightening creams, and depilatory formulations by effectively softening keratin and reshaping disulfide bonds.

What packaging options are standard for this material?

The material is packaged in standard 25kg fiber drums or paper bags, lined internally with a protective PE bag to ensure product safety.

What are the specific storage requirements to maintain quality?

It must be stored in a cool, dry, and well-ventilated location, completely separated from oxidizing agents to maintain stability and performance.