Buy Ammonium Thioglycolate CAS 5421-46-5 Factory, Product

Chemical Name: Ammonium thioglycolate 
CAS No.: 5421-46-5
Molecular Formula: C2H4O2S.H3N
Molecular Structure:

Molecular Weight:109.15
Appearance:Colorless liquid 
Sample:Free samples are available
Melting point: 139-139.5 ° C
Boiling point: 115 ℃ [at 101 325 Pa]
Density: 1.22

Product Description

Typical Properties

Item Specifications
Appearance Colorless or Lavender Pink
Purity 50%; 60%; 70%
pH Value 6.0 - 6.8 (25℃)
Specific Gravity (ρ20, g/cm³) 1.24 (25℃)
Ammonium Thioglycolate (also known as Ammonium Thioethanolate) is a highly efficient reducing thiol compound. Its core function is to cleave the disulfide bonds in keratin, making it a key raw material for cold wave perms, hair straightening, and depilatories. It is also utilized in fields such as metal corrosion inhibition and chemical analysis.

Product Advantages

1. Strong Reducing Power & Precision
Selectively cleaves disulfide bonds in hair keratin, delivering significant softening and reshaping effects.
2. Neutral & Mild
With a pH close to that of human skin and hair, it is less irritating than traditional thioglycolic acid and causes minimal damage to hair quality.
3. Excellent Water Solubility
Easy to formulate into various aqueous solutions and creams, offering good compatibility with different formulations.
4. Flexible Application
Action intensity can be adjusted via concentration and pH, making it suitable for diverse scenarios such as perming, hair straightening, and depilatory uses.
5. Multifunctionality
Beyond hair care, it serves as a metal corrosion inhibitor, chemical analysis reagent, and thiolating agent.

Application Areas

1. Hair Care Industry (Core Application)
Cold Wave Lotions / Perm Solutions: Softens hair keratin and reshapes disulfide bonds to achieve permanent curling; serves as the core reducing agent in cold perms.
Hair Straightening Creams / Relaxers: Cleaves disulfide bonds to soften hair, working in conjunction with neutralizers to achieve permanent straightening.
Depilatory Creams / Lotions: Softens body hair keratin to facilitate easy removal; the preferred choice for mild depilatory products.
Recommended Concentration: 5%–15% for perming/straightening; 2%–8% for depilatory use.
2. Industrial & Other Fields
Metal Corrosion Inhibition: Forms a protective FeS film in high-temperature brine/completion fluids to inhibit carbon steel corrosion (140–200℃).
Chemical Analysis: Used as a masking agent and reducing agent for the photometric determination of ions such as iron, aluminum, silver, and tin.
Material Modification: Serves as a thiolating agent for the preparation of adsorption materials and functional polymers.
Electronic Cleaning: Acts as an auxiliary agent for metal surface treatment and cleaning.

Packaging & Storage

Packaging Specification

25kg/drum, 200kg/drum

Storage Conditions

Store in a cool, dry, and dark place, preferably refrigerated at 2-8℃. Avoid contact with iron/copper.

Frequently Asked Questions (FAQ)

What is the primary function of Ammonium Thioglycolate?

Ammonium Thioglycolate acts as a powerful reducing agent that selectively cleaves disulfide bonds in hair keratin. This allows hair to be reshaped for perming, straightening, or softened for gentle hair removal.

Why is Ammonium Thioglycolate preferred over traditional thioglycolic acid in cosmetics?

It features a neutral to mild pH range (6.0-6.8) which is much closer to human skin and hair pH. This results in significantly less skin irritation and reduced hair damage compared to harsher acid alternatives.

What are the recommended dosage levels for hair formulations?

For cold perms and hair straightening lotions, the recommended concentration is typically between 5% and 15%. For milder depilatory products, a dosage of 2% to 8% is generally advised.

What industrial applications does Ammonium Thioglycolate serve?

Beyond cosmetics, it is utilized as a metal corrosion inhibitor in high-temperature brine solutions, a masking agent in chemical analysis, a thiolating agent for polymer modification, and a cleaning agent for electronic metal surfaces.

How should Ammonium Thioglycolate be properly stored?

It should be kept in a cool, dry, and dark environment, ideally refrigerated at 2-8°C. It is critical to keep the product out of direct contact with metals like iron and copper to prevent degradation.

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