Direct factory supply of pharmaceutical intermediates, cosmetic actives, and high-performance antimicrobial ingredients.
An in-depth chemical and procurement guide on Chloroxylenol (4-Chloro-3,5-dimethylphenol, CAS 88-04-0) manufactured by China’s fine chemical leaders.
4-Chloro-3,5-dimethylphenol, universally known in commercial procurement as PCMX (CAS 88-04-0), is a broad-spectrum, highly efficient halogenated phenolic antimicrobial agent. Recognized globally for its bactericidal, fungicidal, and virucidal properties, PCMX functions primarily by rupturing microbial cell walls, denaturing critical cellular proteins, and inactivating key metabolic enzyme systems. Unlike legacy phenols, PCMX delivers exceptional antimicrobial potency paired with low systemic mammalian toxicity, rendering it the active pharmaceutical ingredient (API) and biocide of choice across medical hygiene, personal care formulations, household surface disinfectants, and industrial material preservation.
The technical benchmark below highlights the strict specification parameters guaranteed by premium Chinese manufacturers such as JIMPOCHEM CO., LTD.
| Parameter / Property | Technical Specification (BP / USP / EP Standard) | Testing Method / Analytical Equipment |
|---|---|---|
| Chemical Name | 4-Chloro-3,5-dimethylphenol / 4-Chloro-3,5-xylenol | IUPAC Nomenclature |
| CAS Registry Number | 88-04-0 | CAS Index |
| Molecular Formula / Weight | C8H9ClO / 156.61 g/mol | Mass Spectrometry (MS) |
| Appearance | White to off-white crystalline powder or flakes | Visual Inspection |
| Assay (Purity) | ≥ 99.0% (Premium grade ≥ 99.5%) | Gas Chromatography (GC-FID) / HPLC |
| Melting Point Range | 114.0 °C – 116.5 °C | Capillary Melting Point Apparatus |
| Water / Moisture Content | ≤ 0.5% | Karl Fischer Titration |
| Residue on Ignition (Ash) | ≤ 0.1% | Gravimetric Analysis (800°C) |
| Free 3,5-Dimethylphenol | ≤ 0.2% | Chromatographic Impurity Profile |
| Tetrachlorvinphos / Related Chlorinated Impurities | Controlled within USP/BP limit guidelines | GC-MS Analysis |
| Solubility Profile | Practically insoluble in water (0.03% at 20°C); freely soluble in ethanol, ether, terpenes (pine oil), and alkaline solutions | Dissolution Testing |
China’s emergence as the global epicenter for PCMX manufacturing is rooted in complete industrial chain integration, sophisticated catalytic synthesis technologies, and rigorous environmental compliance within dedicated chemical zones.
Chinese manufacturers benefit from direct, localized access to key synthetic precursors such as 3,5-xylenol and sulfuryl chloride or elemental chlorine gas. This backward integration insulates global buyers from raw material price volatility and guarantees uninterruptible production cycles.
Advanced continuous-flow reactors and proprietary catalytic systems enable precise mono-chlorination at the para-position of 3,5-xylenol. This minimizes unwanted ortho-chlorinated isomers and polychlorinated byproducts, yielding high-purity crystalline PCMX exceeding 99.5%.
Modern chemical parks in Shandong, such as JIMPOCHEM's 500+ acre industrial complex in Jinan, feature automated wastewater treatment, VOC recovery systems, and digital carbon-tracking. This guarantees compliant, long-term supply without environmental shutdown risks.
PCMX’s versatility spans diverse sector applications due to its stability across broad temperature ranges, resistance to light degradation, and synergism with non-ionic surfactants and essential oils.
In surgical pre-operative skin antiseptics, wound cleansing liquids, and medical instrument disinfectants, PCMX demonstrates rapid knock-down against Gram-positive (*Staphylococcus aureus*, including MRSA) and Gram-negative (*Escherichia coli*, *Pseudomonas aeruginosa*) pathogens.
PCMX is the primary active in household liquid disinfectants (e.g., pine-oil solubilized concentrates). It is also incorporated into antibacterial soaps, anti-dandruff shampoos, and body washes due to its gentle dermatological profile when correctly solubilized.
Beyond personal hygiene, PCMX serves as an effective wet-state preservative in metalworking fluids, industrial adhesives, coatings, inks, leather processing emulsions, and textile finishing agents, preventing microbial biodeterioration.
Because pure PCMX has low water solubility, optimal formulation relies on micellar solubilization. Combining PCMX with isopropyl alcohol, terpene solvents (pine oil), or potassium ricinoleate creates microemulsion concentrates that bloom into milk-white emulsions upon water dilution.
Established in 2010 and headquartered in the Chemical Industry Park of Jinan City, Shandong Province, JIMPOCHEM CO., LTD covers an area of over 500 acres. As a premier chemical raw material manufacturer integrating R&D, continuous production, global sales, and technical service, our core expertise centers on high-end fine chemicals, biocide actives, and cosmetic raw materials.
Holding ISO 9001 Quality Management System Certification and ISO 14001 Environmental Management Certification, we operate robust production pipelines serving over 5,000 international companies across 200+ countries in Europe, the Americas, Southeast Asia, the Middle East, and Oceania.
Sourcing PCMX internationally requires stringent compliance verification. B2B buyers must evaluate technical dossiers, batch-to-batch consistency, impurity profiles, and international chemical transport certifications.
Every shipment is backed by a batch-specific Certificate of Analysis (CoA), full GC-MS spectrum verification, and digital raw material tracking from precursor synthesis to final drum filling.
We provide global clients with complete regulatory packages including EU REACH registration data, US FDA OTC drug master file support, Safety Data Sheets (SDS) in 20+ languages, and ISO compliance dossiers.
Standard packaging includes 25kg cardboard drums with moisture-barrier PE liners or 500kg flexible intermediate bulk containers (FIBC / Super Sacks). Palletization complies with ISPM-15 heat treatment standards.
Expert answers regarding Chloroxylenol technical parameters, safety profiles, regulatory compliance, and bulk supply chain logistics.
High-purity ingredients for personal care, healthcare, and industrial applications direct from our Shandong manufacturing facilities.
JIMPOCHEM
