China Bemotrizinol CAS 187393-00-6 Factories & Products

Comprehensive Industrial Technical Whitepaper, Molecular Engineering Breakthroughs, and Global OEM/ODM Supply Chain Analysis

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Executive Whitepaper: Bemotrizinol (CAS 187393-00-6) Market Dynamics & Chemical Mechanics

An in-depth study on the gold-standard broad-spectrum photostable organic UV absorbing technology produced by China's advanced synthesis hubs

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Photochemical Performance Profile

Bemotrizinol (INCI: Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, CAS 187393-00-6) represents the peak of oil-soluble organic UV filters. Engineered with a triazine core and dual hydroxyphenyl side-chains, it delivers exceptional dual-band extinction coefficients across both UVA (320–400 nm) and UVB (290–320 nm) domains, featuring twin absorption peaks at 310 nm and 343 nm.

Key Photostability Mechanism: Unlike legacy absorbers such as Avobenzone, Bemotrizinol dissipates absorbed photon energy via rapid intramolecular proton transfer (ESIPT) without undergoing irreversible photochemical degradation. It retains >98% of its protective efficacy even after 50 MEDs of intense UV exposure.
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Physicochemical Specifications

For chemical formulators and global procurement managers, strict adherence to purity metrics is paramount for anti-crystallization and emulsion stability:

  • Chemical Formula: C38H49N3O5
  • Molecular Weight: 627.81 g/mol
  • Appearance: Light yellow to off-white crystalline powder
  • Purity (HPLC): ≥ 99.0% (Single Impurity ≤ 0.3%)
  • Melting Point: 80.0°C – 85.0°C
  • Extinction Coefficient (E1/1 at 343nm): ≥ 810
  • Heavy Metal Residue: ≤ 10 ppm (As ≤ 2 ppm, Pb ≤ 5 ppm)
16+
Years Chemical Expertise
500+
Acres Industrial Park Base
200+
Global Export Markets
5000+
International B2B Clients

China Factory 4.0: Modern Manufacturing & Supply Chain Resilience

How state-of-the-art chemical synthesis technology in Jinan, Shandong drives global market stability and competitive advantage

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Automated Synthesis & Batch Precision

JIMPOCHEM CO., LTD operates digitalized batch-control reactors within the Chemical Industry Park of Jinan City. Automated thermal regulating units control the condensation reaction between cyanuric chloride and substituted resorcinol, eliminating local overheating and suppressing byproduct formation.

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Green Chemistry & EHS Leadership

Aligning with China’s national "Dual-Carbon" target, our factories utilize closed-loop solvent recovery systems achieving a 96.5% recycling efficiency for organic solvents. Advanced catalytic wastewater oxidation units ensure zero untreated discharge, ensuring reliable, eco-friendly long-term manufacturing operations.

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Supply Chain Security & Vertical Integration

By controlling precursor manufacturing (such as 2,4-bis(4-methoxyphenyl)-6-chloro-1,3,5-triazine), our operations bypass raw material shortages, offering international personal care brands guaranteed lead times, consistent batch purity, and robust protection against global price volatility.

Comprehensive Quality Control Standards (COA Data)

Validated via rigorous analytical methods (HPLC, GC-MS, ICP-OES) under certified ISO 9001:2015 quality systems

Parameter Test Item Target Standard (COA Limit) Typical Batch Analytical Results Analytical Method
Chemical Identification Conforms to Standard Spectrum Conforms FTIR / Proton NMR
Assay (Purity by HPLC) ≥ 99.0% 99.6% – 99.8% HPLC (Chromatographic Purity)
Specific Extinction Coefficient (E1/1) ≥ 810 at 343 nm ± 2 nm 825 – 840 UV-Vis Spectrophotometry (Ethanol)
Loss on Drying ≤ 0.50% 0.18% 105°C Constant Weight
Melting Range 80.0°C – 85.0°C 81.5°C – 83.2°C Capillary Melting Apparatus
Residual Solvents Toluene ≤ 890 ppm, Methanol ≤ 3000 ppm Below Detection Limit (< 10 ppm) Headspace GC-FID
Heavy Metals Total ≤ 10.0 mg/kg < 2.0 mg/kg ICP-MS

Technical Roadmap & Next-Gen Sunscreen Formulation Architecture

Solving complex formulation engineering challenges through synergistic chemistry and micro-dispersion developments

Synergistic Photostabilization Engineering

Modern broad-spectrum sunscreen design relies heavily on Bemotrizinol to stabilize photo-labile molecules. When blended with Avobenzone (Butyl Methoxydibenzoylmethane) or Octyl Methoxycinnamate (OMC), Bemotrizinol transfers singlet excitation energy safely, stopping the photodegradation cascade:

  • Avobenzone Stabilization: Prevents keto-enol photo-tautomerism breakdown, maintaining high UVA protection over 8 hours.
  • SPF Boosting Synergy: Combining 2% Bemotrizinol with 3% Ethylhexyl Triazone (EHT) achieves SPF values exceeding standalone 10% single-filter benchmarks.
  • Blue Light / HEV Shielding: Hybrid formulas integrating micronized Hydroxyapatite or Titanium Dioxide with Bemotrizinol mitigate High-Energy Visible light degradation.
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Solubility Optimization & Texture Engineering

Because Bemotrizinol is a crystalline solid with high lipid affinity, proper solvent selection is crucial to prevent re-crystallization during low-temperature storage:

  • Optimal Solvents: Highly soluble in polar synthetic esters like C12-15 Alkyl Benzoate (up to 14% at 25°C), Isopropyl Myristate (CAS 110-27-0), and Diisopropyl Adipate.
  • Emulsion Processing: Must be completely dissolved in the oil phase at 75°C–80°C prior to emulsification.
  • Sensory Enhancement: Non-sticky after-feel, making it ideal for daily light skin-feel fluids, water-gel cushions, and high-SPF sport lotions.

Macro Industry Solutions & Sector Applications

Providing specialized active raw material solutions across diverse manufacturing industries

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Personal Care & Cosmetics

Integrated into anti-aging daily creams, high-protection sunscreens, color cosmetics, and foundation fluids. Protects skin matrix proteins (collagen, elastin) against photo-induced ROS formation and premature aging.

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Pharmaceutical & Topical Actives

Used in dermatological post-procedure repair serums and barrier creams requiring absolute photostability. Works synergistically with topical actives like Tranexamic Acid and Ascorbyl Glucoside to prevent UV-triggered hyperpigmentation.

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Specialty Polymers & Coatings

Incorporated as an advanced light stabilizer for high-end optical films, clear polyurethane coatings, and automotive coatings where extreme UV resistance and non-yellowing characteristics are mandatory.

Global Regulatory Matrix & Safety Profile

Fully compliant with international chemical registration frameworks and consumer safety regulations

EU REACH Registered

Full REACH compliance allows seamless importation and distribution across all European Union member states with complete dossiers for ecotoxicology and human safety.

China NMPA Standard

Listed under China’s Safety and Technical Standard for Cosmetics (2015 edition) with a maximum authorized usage limit of 10% in cosmetic products.

US FDA GRASE Status

Currently undergoing FDA OTC monograph review under the US Sunscreen Innovation Act, widely used in non-US formulations and global export stock keeping units (SKUs).

Ecological Safety

Non-toxic to aquatic ecosystems, offering a safer alternative to coral-reef-threatening traditional filters such as Oxybenzone (Benzophenone-3) and Octinoxate.

Corporate Heritage: JIMPOCHEM CO., LTD

Your designated chemical service provider — Integrated R&D, Automated Production, and Technical Support

16 Years of Excellence in Fine Chemicals

Established in 2010 and headquartered in the prestigious Chemical Industry Park of Jinan City, Shandong Province, JIMPOCHEM CO., LTD covers an expansive area of over 500 acres. We are a professional fine chemical manufacturer integrating research and development, mass production, technical service, and direct global distribution.

Our core leadership comprises industry veterans with over 10 to 16 years of chemical engineering experience. Adhering strictly to ISO quality and environmental management system certifications, we deliver one-stop procurement solutions to over 5,000 corporate clients across 200 countries and regions worldwide.

Mission & Vision: To lead global fine chemical technological innovation through green development, delivering long-term value, raw material traceability, and unmatched supply resilience to our global partners.

Global Procurement & Shipping Specifications

Standardized packaging solutions ensuring raw material structural integrity during transoceanic transit

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Standard Industrial Packaging

25 kg Fiber Drums with double polyethylene inner liners, sealed under nitrogen purge to prevent moisture absorption and photo-oxidation. Custom 500 kg super-sacks available for enterprise-level automated production lines.

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Storage & Shelf-Life Protocol

Store in original unopened packaging in a cool, dry, well-ventilated warehouse away from direct sunlight and heat sources (temperatures below 30°C). Guaranteed shelf-life of 24 months under recommended storage conditions.

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Logistics & Export Customs Compliance

Non-hazardous chemical classification for sea, air, and rail transport (IMDG/IATA compliant). Complete export documentation including Certificate of Analysis (COA), Safety Data Sheet (MSDS/SDS), and Country of Origin certificate provided per shipment.

Frequently Asked Questions (Technical & Procurement FAQ)

Addressing core technical questions from cosmetic chemists, procurement directors, and compliance officers

Q1 What makes Bemotrizinol superior to conventional UV absorbers like Avobenzone?
Bemotrizinol provides exceptional photostability and dual UVA+UVB broad-spectrum coverage. While Avobenzone rapidly degrades under solar radiation unless fortified with stabilizers, Bemotrizinol efficiently dissipates UV energy via intramolecular energy transfer without undergoing molecular breakdown, while simultaneously stabilizing co-formulated UV filters.
Q2 What is the recommended maximum dosage of Bemotrizinol in cosmetic formulations?
Regulatory upper limits vary by geographic jurisdiction. In the European Union, China (NMPA), Australia (TGA), and Japan, the maximum allowable concentration in topical cosmetic formulations is 10%. In functional sunscreen applications, typical usage rates range between 1.5% and 5.0% to achieve optimal SPF/PA synergy.
Q3 How do formulators solve Bemotrizinol recrystallization in water-in-oil or oil-in-water emulsions?
Recrystallization is prevented by selecting polar emollient esters with high dissolving capacity, such as C12-15 Alkyl Benzoate, Isopropyl Myristate (CAS 110-27-0), or Dibutyl Adipate. Ensure the oil phase is thoroughly heated to 80°C until all crystalline particles are completely dissolved prior to joining the aqueous phase.
Q4 What purity grade does JIMPOCHEM guarantee for Bemotrizinol CAS 187393-00-6?
JIMPOCHEM manufactures high-grade Bemotrizinol with a minimum HPLC purity of 99.0%. Every batch undergoes stringent analytical verification, ensuring single individual impurities remain strictly below 0.3%, with controlled residual solvent limits compliant with international cosmetic guidelines.
Q5 Is Bemotrizinol environmentally safe and reef-conscious?
Yes. Unlike older UV filters such as Oxybenzone and Octinoxate—which have been banned in Hawaii and Palau due to coral bleaching concerns—Bemotrizinol exhibits low bioaccumulation potential and negligible ecotoxicity to aquatic organisms, making it a key component for eco-friendly, reef-safe sunscreen lines.
Q6 Can Bemotrizinol be incorporated into water-phase-only formulations?
Bemotrizinol is inherently oil-soluble. To incorporate it into transparent aqueous gels or alcohol-free sprays, chemists must utilize specialized micro-encapsulation techniques or pre-solubilize the active within high-efficiency non-ionic solubilizers prior to water dispersion.
Q7 What is the Minimum Order Quantity (MOQ) for international corporate clients?
Our standard commercial factory MOQ starts at 25 kg (1 fiber drum). For pilot-scale trial testing and initial product development phases, sample quantities (1 kg to 5 kg) are available upon qualified technical request.
Q8 How does JIMPOCHEM manage batch-to-batch quality consistency?
We employ automated DCS (Distributed Control Systems) across our synthesis lines in Jinan. Every production batch undergoes full-spectrum testing in our centralized QA/QC laboratory, with batch retain samples maintained for 36 months to ensure full historical data traceability.
Q9 What regulatory documentation accompanies commercial shipments?
All commercial deliveries include a batch-specific Certificate of Analysis (COA), 16-section Safety Data Sheet (SDS/MSDS), Certificate of Origin (COO), REACH compliance statements, and BSE/TSE-free certification.
Q10 What are the lead times for global sea freight dispatch?
Standard dispatch for stocked material occurs within 7 to 10 business days following order confirmation. Custom synthesized orders or large-scale multi-container contracts typically require a 2 to 3 week manufacturing turn-around time.

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