Explore our flagship, high-purity chemical portfolio manufactured under rigorous ISO & cGMP standards for worldwide delivery.
Sodium octanoate powder, also systematically designated as Sodium Caprylate (CAS Number: 1984-06-1; EC Number: 217-850-5), is the sodium salt of the medium-chain saturated aliphatic C8 fatty acid (caprylic acid). Characterized by its distinct amphiphilic structure—comprising an 8-carbon hydrophobic aliphatic chain coupled with a highly polar hydrophilic sodium carboxylate headgroup—sodium octanoate serves as an irreplaceable functional agent across biopharmaceutical processing, diagnostic formulation, personal care science, and high-end industrial synthesis.
In biopharmaceutical applications, Sodium Octanoate acts as an essential specific thermal stabilizer and lipophilic protectant for Human Serum Albumin (HSA) and plasma-derived immunoglobulins during heat-treatment pasteurization cycles (e.g., 60°C for 10 hours) designed for viral inactivation. Its high binding affinity to hydrophobic pockets in plasma proteins prevents denaturation, aggregation, and structural unfolding without altering biological efficacy.
| Parameter / Specification Item | Pharma Grade / Bioprocess Standard | Industrial / Fine Chemical Standard | Testing Methodology |
|---|---|---|---|
| Chemical Name | Sodium Octanoate / Sodium Caprylate (C8H15NaO2) | IUPAC Nomenclature | |
| CAS Registry Number | 1984-06-1 | CAS Index | |
| Appearance | White to off-white crystalline powder | White fine powder or granules | Visual Inspection |
| Assay (Dry Basis) | ≥ 99.5% | ≥ 98.5% | Potentiometric Titration / HPLC |
| Bacterial Endotoxins | < 0.10 EU/mg (Ultra-low Endotoxin) | N/A | LAL Kinetic Chromogenic Test |
| Heavy Metals (as Pb) | ≤ 5 ppm | ≤ 10 ppm | ICP-MS / AAS |
| Loss on Drying (105°C) | ≤ 0.5% | ≤ 1.0% | Thermogravimetric Analysis |
| pH (5% Aqueous Solution) | 8.0 – 10.5 | 7.5 – 11.0 | pH Glass Electrode |
| Solubility in H2O | Freely soluble (>100 g/L at 20°C) | Soluble | Gravimetric Method |
At JIMPOCHEM CO., LTD (established in 2010 in the Chemical Industry Park of Jinan City, Shandong Province), our manufacturing framework represents the pinnacle of modern fine chemical synthesis. Spanning over 500 acres, our smart facility operates under strict cGMP and ISO 9001/14001/45001 management regimes, delivering unmatched scalability, continuous process control, and batch-to-batch consistency.
Our primary production line utilizes high-purity natural caprylic acid neutralization with ultra-pure sodium hydroxide in closed-loop stainless steel reactors (316L). Real-time Distributed Control Systems (DCS) monitor reaction temperature, stoichiometric molar balances, and crystallization rates to eliminate residual unreacted fatty acids and ensure near-100% purity.
For biopharmaceutical grades, solutions undergo multi-stage ceramic ultra-filtration and carbon-bed depyrogenation to remove particulate matter, trace organic impurities, and pyrogens. Crystallization occurs in positive-pressure Class 100,000 cleanroom environments to guarantee compliance with parenteral injection standards.
To meet diverse customer processing requirements, JIMPOCHEM offers tailored particle-size distribution (PSD). Utilizing fluid-bed jet milling and modern granulators, we produce both high-flow non-dusting granules and fine powder (80-200 mesh) with rapid dissolution kinetic profiles.
Sodium octanoate powder is more than a simple chemical salt; it is a critical functional enabler in multiple high-tech industries. The following matrix details how global procurement managers and process chemical engineers leverage sodium caprylate across diverse industrial sectors.
Pasteurization Stabilization: During the Cohn fractionation process, Human Serum Albumin (HSA) must be pasteurized at 60°C for 10 hours to deactivate blood-borne pathogens (HIV, HBV, HCV). Adding pharmaceutical-grade sodium octanoate (CAS 1984-06-1) at controlled concentrations (typically 0.08 to 0.16 mmol/g albumin) protects the tertiary protein conformation against heat denaturation.
Enzyme & Protein Preservation: Serves as a stabilization reagent in recombinant protein isolation, antibody-drug conjugate (ADC) processing, and diagnostic enzyme liquid formulations.
Lipid Nutrient Supplement: Mammalian cell lines (CHO, HEK293, Vero) utilized in biomanufacturing require bio-available fatty acids for cell membrane synthesis. Sodium octanoate acts as a water-soluble C8 lipid donor in serum-free and chemically defined cell culture media, optimizing cell viability and monoclonal antibody yield.
Co-Surfactant & Antimicrobial Booster: In green cosmetic engineering, sodium caprylate exhibits inherent broad-spectrum antimicrobial booster activity against Gram-positive/Gram-negative bacteria and fungi. It enhances preservative efficacy, acts as a mild surfactant, and improves skin feel in cleansers, creams, and lotions.
Phase Transfer Catalyst & Flotation Reagent: Serves as an efficient phase transfer catalyst in organic synthesis, metal extraction, electroplating formulations, and specialized mineral flotation processes where precise lipophilic balance is required.
The global market demand for high-purity C8 salts is experiencing structural growth, driven by advances in mRNA vaccine storage buffers, continuous bioprocessing, and eco-friendly chemical manufacturing. JIMPOCHEM’s R&D division is executing a multi-phase innovation roadmap designed to deliver unprecedented value to global buyers:
Developing next-generation sub-nanofiltration technology to reduce endotoxin levels below 0.01 EU/mg, tailored specifically for advanced cell and gene therapy (CGT) culture media and parenteral formulations.
Transitioning raw material procurement toward 100% RSPO-certified bio-based caprylic acid sources, coupled with solar-powered continuous crystallization loop systems to achieve net-zero carbon chemical synthesis.
Engineering spherical micro-granules with optimized angle of repose (<30°) to facilitate automated bulk powder feeding systems in modern automated pharma production lines.
Procuring chemical raw materials globally requires guaranteed stability, cost optimization, and transparent risk mitigation. As a designated chemical service provider for Fortune 500 enterprises, JIMPOCHEM provides structural procurement security through:
We offer standard 25 kg fiber drums with double PE liners, 500 kg jumbo bags, and custom nitrogen-purged vacuum packaging for moisture-sensitive shipments. Our strategic location near Qingdao Port ensures seamless sea freight, air express (DHL/FedEx sample dispatch within 24 hours), and door-to-door DDP logistics.
To hedge against raw material price volatility, JIMPOCHEM supports global strategic partners with 3-to-12-month fixed-price supply agreements and dedicated safety stock buffering in regional warehouses across Europe and North America.
Navigating complex international chemical regulations demands complete compliance documentation. JIMPOCHEM’s regulatory affairs team provides complete regulatory validation dossiers to streamline client audit and approval processes.
Full EU-REACH registration, UK-REACH compliance, and US EPA TSCA inventory listing for seamless import clearance.
Comprehensive Drug Master File (DMF) documentation, cGMP validation packages, and change-control notification protocols.
Certified 100% plant-derived fatty acid raw materials with full Kosher and Halal annual certifications.
Batch-number traceability linking final CoA metrics directly to raw material lot codes, reactor operational data, and QC spectrum analysis.
JIMPOCHEM CO., LTD was established in 2010 and is headquartered in the Chemical Industry Park of Jinan City, Shandong Province. Integrating research and development, continuous automated production, global sales, and technical consulting services, we specialize in high-end fine chemicals and cosmetic raw materials. Our core team comprises industry experts with over 16 years of hands-on experience, providing tailored technical guidance, formula optimization, and custom synthesis solutions.
Discover our extended catalog of high-purity organic compounds, active ingredients, and fluorinated solvents available for global bulk supply.
JIMPOCHEM
