China Azelaic Acid CAS 123-99-9 - Quality Crystalline Powder from China Suppliers & Factory Factory, Product

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Chemical Name: Azelaic acid
CAS No.: 123-99-9
Molecular Formula: C9H16O4

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Molecular Weight: 188.22
Appearance: Crystalline powder
Sample: Free samples are available upon request.

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Key Properties: Azelaic acid has a melting point of approximately 106°C and a boiling point of 286°C at 100 mmHg. It is slightly soluble in cold water (about 2.4 g/L at 20°C) but freely soluble in hot water, ethanol, propylene glycol, and ethyl acetate. This compound is chemically stable, demonstrating resistance to oxidation and decomposition. It undergoes typical reactions associated with dibasic carboxylic acids, such as salt formation and esterification.

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As a leading manufacturer and supplier of Azelaic acid in China, our factory guarantees high-quality products that meet global standards. We invite you to explore our offerings and take advantage of our free sample provisions.

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Product Description

Typical Properties
Item Specifications
Appearance Crystalline powder
Moisture ≤0.2%
Assay ≥98%
Acid value 585–610
Melting point 105–110℃
Particle size ≥60 mesh
Plumbum ≤1 ppm
Arsenic ≤1 ppm
Chromium ≤1 ppm
Color ≥ 95%
Color ≥ 99%
Application
1 Dermatology / Skincare
Acne Treatment

Inhibits Cutibacterium acnes (formerly P. acnes), regulates follicular keratinization, and exerts anti-inflammatory effects. Common formulations include 15% gel and 20% cream; recommended for topical use by the Chinese Guidelines for Acne Treatment.

Whitening & Mark Fading

Selectively inhibits tyrosinase in abnormal melanocytes to fade acne marks, post-inflammatory hyperpigmentation (PIH), and melasma. Its irritation potential is significantly lower than that of tretinoin or high-concentration AHAs.

Oil Control & Soothing

Inhibits 5α-reductase to reduce sebum secretion. Suitable for oily, acne-prone skin and as adjunctive care for rosacea.

Common Dosage Forms

Gels, creams, moisturizers, serums, and masks.

10%
Daily skincare (suitable for sensitive skin)
15%
Mainstay for acne treatment
20%
Pharmaceutical grade (requires tolerance building)
2 Industrial Chemical Sector
  • Plasticizers: Synthesis of Dioctyl Azelate (DOZ), Diisooctyl Azelate, etc. Used in PVC and rubber, offering excellent heat resistance, cold resistance, and electrical insulation properties; suitable for products in low-temperature environments.
  • Lubricants / Synthetic Oils: Used as components for precision instruments and aviation hydraulic fluids.
  • Coatings / Resins: Modified polyesters and alkyd resins to improve coating flexibility and weatherability.
3 Other Applications

Feed additives, electroplating brighteners, polymer crosslinking agents, etc.

Application Areas
1 Hair Care Industry (Core Application)
  • Cold Wave Lotions / Perm Solutions: Softens hair keratin and reshapes disulfide bonds to achieve permanent curling; serves as the core reducing agent in cold perms.
  • Hair Straightening Creams / Relaxers: Cleaves disulfide bonds to soften hair, working in conjunction with neutralizers to achieve permanent straightening.
  • Depilatory Creams / Lotions: Softens body hair keratin to facilitate easy removal; the preferred choice for mild depilatory products.
  • Recommended Concentration: 5%–15% for perming/straightening; 2%–8% for depilatory use.
2 Industrial & Other Fields
  • Metal Corrosion Inhibition: Forms a protective FeS film in high-temperature brine/completion fluids to inhibit carbon steel corrosion (140–200℃).
  • Chemical Analysis: Used as a masking agent and reducing agent for the photometric determination of ions such as iron, aluminum, silver, and tin.
  • Material Modification: Serves as a thiolating agent for the preparation of adsorption materials and functional polymers.
  • Electronic Cleaning: Acts as an auxiliary agent for metal surface treatment and cleaning.
Package & Storage
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Package 25kg fiber drums / paper bags (lined with PE bag)
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Storage Store in a well-ventilated, cool, and dry place; keep separate from oxidizing agents.
Frequently Asked Questions
Q What is the recommended concentration of this ingredient for acne treatment?
For acne treatment, a 15% concentration is considered the mainstay formulation. A 10% concentration is suitable for daily skincare and sensitive skin, while a 20% pharmaceutical-grade concentration requires a tolerance-building period before regular use.
Q How does this ingredient help with skin whitening and hyperpigmentation?
It selectively inhibits tyrosinase activity in abnormal melanocytes, helping to fade acne marks, post-inflammatory hyperpigmentation (PIH), and melasma. Compared to tretinoin or high-concentration AHAs, its irritation potential is significantly lower, making it suitable for a wider range of skin types.
Q What are the industrial applications of this product?
In the industrial sector, it is used for the synthesis of plasticizers such as Dioctyl Azelate (DOZ) for PVC and rubber, as a component in precision instrument lubricants and aviation hydraulic fluids, and as a modifier for polyesters and alkyd resins to enhance coating flexibility and weatherability.
Q What concentration is recommended for use in perm and hair straightening products?
For perming and hair straightening applications, a concentration of 5%–15% is recommended. For depilatory cream and lotion formulations, a lower concentration of 2%–8% is advised for effective yet gentle performance.
Q What are the packaging and storage requirements for this product?
The product is packaged in 25kg fiber drums or paper bags, each lined with a PE inner bag to ensure protection during transport and storage. It should be stored in a well-ventilated, cool, and dry environment, and must be kept separate from oxidizing agents to maintain product integrity.
Q What purity and quality standards does this product meet?
The product meets an assay of ≥98%, with moisture content ≤0.2% and heavy metal impurities (lead, arsenic, chromium) each controlled at ≤1 ppm. The melting point is 105–110℃ and particle size is ≥60 mesh, ensuring consistent high-quality performance across both cosmetic and industrial applications.

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