N-(3-Aminopropyl)morpholine (Chemical Abstracts Service Registry Number: 123-00-2), also widely known in industrial nomenclature as 4-Morpholinepropanamine, APM, or N-(3-Aminopropyl)tetrahydro-1,4-oxazine, is a bifunctional organic heterocycle containing both a tertiary amine within a morpholine ring structure and a primary aliphatic amine termination. This unique dual-functionality grants the compound exceptional reactivity, thermal resistance, catalytic effectiveness, and solvency performance across a diverse range of high-performance polymer formulations, specialty agricultural inputs, water processing chemistry, and pharmaceutical synthesis networks.
As global industrial manufacturing advances toward higher chemical efficiency, reduced curing cycle times, and stringent environmental sustainability compliance, high-purity CAS 123-00-2 has emerged as an essential building block. JIMPOCHEM CO., LTD, operating out of our state-of-the-art chemical complex in China, manufactures industrial-grade N-(3-Aminopropyl)morpholine under continuous catalytic synthesis systems, delivering consistent purity exceeding 99.5% by GC assay.
Below is the validated technical specification benchmark for CAS 123-00-2 produced directly by JIMPOCHEM facilities:
| Property Parameter | Standard Specification Unit | Guaranteed Industrial Value | Testing Standard Method |
|---|---|---|---|
| Chemical Name | N-(3-Aminopropyl)morpholine | Structural Formula: C7H16N2O | IUPAC / CAS Nomenclature |
| CAS Registry Number | 123-00-2 | EINECS: 204-590-2 | International Registry |
| Appearance / State | Visual Inspection | Clear, Colorless to Light Straw Liquid | ASTM D1209 |
| Purity (GC Assay) | % (m/m) | ≥ 99.5% | Gas Chromatography (FID) |
| Water Content (Karl Fischer) | % (m/m) | ≤ 0.15% (Max 0.20%) | ASTM E203 / ISO 760 |
| Color Scale | Pt-Co / Hazen | ≤ 15 Hazen | GB/T 3143 / ASTM D1209 |
| Total Amine Value | mg KOH/g | 760.0 - 775.0 mg KOH/g | Acid-Base Potentiometric Titration |
| Density at 20°C | g/cm³ | 0.985 - 0.990 g/cm³ | ISO 12185 Pycnometer |
| Boiling Point Range | °C at 760 mmHg | 224.0 °C - 228.0 °C | ASTM D1078 |
| Flash Point (Closed Cup) | °C | 98.5 °C | ASTM D93 / ISO 2719 |
JIMPOCHEM CO., LTD is situated in the national-level Chemical Industry Park of Jinan City, Shandong Province, spanning over 500 acres of modernized chemical manufacturing infrastructure. Our location allows immediate pipeline access to primary petrochemical feedstock including morpholine and acrylonitrile, completely neutralizing raw material supply bottlenecks and insulating global clients from regional price volatility.
By bypassing intermediaries and commercial agents, direct sourcing of CAS 123-00-2 from our Shandong production base provides multinational procurement buyers with a distinct economic edge. Scale economics, coupled with energy-efficient heat integration loops within our distillation trains, allow us to offer competitive direct FOB/CIF container pricing while guaranteeing premium technical standards.
In heavy-duty industrial anti-corrosion coatings, civil engineering flooring resins, structural adhesives, and electronics potting compounds, N-(3-Aminopropyl)morpholine acts as an exceptional curing agent and catalytic hardener promoter.
The tertiary amine core of CAS 123-00-2 functions as a balanced blowing/gelling catalyst in rigid, flexible, and microcellular polyurethane formulations, as well as elastomeric sealants.
With rising global focus on decarbonization and refinery efficiency, CAS 123-00-2 serves as a specialized gas treating agent and steam condensate line neutralizer.
Acts as a pivotal intermediate for synthesizing active pharmaceutical ingredients (APIs), active plant protection chemicals, and antimicrobial agents.
Utilized to formulate cationic wetting agents, fabric softeners, and level-dyeing auxiliaries for modern synthetic fiber treatment.
High-purity grades of CAS 123-00-2 are integrated into chemical mechanical polishing (CMP) slurries and photoresist stripper cleaning fluids.
Formulators frequently encounter challenges balancing cure speeds, glass transition temperatures ($T_g$), mechanical flexibility, and surface appearance when designing epoxy hardener packages. The table below presents comparative technical laboratory data benchmarking N-(3-Aminopropyl)morpholine (CAS 123-00-2) against conventional aliphatic amines such as Diethylenetriamine (DETA), Triethylenetetramine (TETA), and Isophoronediamine (IPDA).
| Performance Metric | CAS 123-00-2 (APM) | DETA (CAS 111-40-0) | TETA (CAS 112-24-3) | IPDA (CAS 2855-13-2) |
|---|---|---|---|---|
| Amine Hydrogen Equivalent Wt. (AHEW) | 72.1 g/eq | 20.6 g/eq | 24.4 g/eq | 42.6 g/eq |
| Pot Life at 25°C (100g Mass) | 45 - 55 mins (Extended) | 15 - 20 mins (Short) | 20 - 25 mins | 60 - 75 mins |
| Amine Blush Resistance | Excellent (High) | Poor (High blushing) | Moderate | Good |
| Flexural Modulus / Toughness | Superior (Ether ring) | Rigid / Brittle | Moderate | High Rigid |
| Color Stability (UV / Aging) | Low Yellowing | High Yellowing | Moderate Yellowing | Low Yellowing |
| Vapor Pressure / Odor Profile | Low Volatility (<0.05 mmHg) | High Odor / Volatile | Moderate Volatility | Low Volatility |
Key Formulation Takeaway: Incorporating CAS 123-00-2 into amine hardener co-curing packages allows formulators to reduce brittle micro-cracking while completely eliminating surface carbamation defects standard in DETA/TETA systems, making it the preferred chemical modifier for premium epoxy floorings and marine protective coatings.
JIMPOCHEM guarantees full regulatory compliance across international target markets for CAS 123-00-2:
Every shipment is accompanied by multi-lingual SDS documentation conforming to GHS Revision 8 regulations:
Our quality management infrastructure ensures absolute batch integrity:
We provide validated, heavy-duty export packaging engineered to withstand ocean transit stress and maintain inert product purity:
Navigating global logistics bottlenecks requires dedicated supply chain management:
The global amine intermediate market is undergoing a structural transition driven by net-zero sustainability mandates, stricter REACH environmental chemical evaluations, and the rapid expansion of renewable energy infrastructure. Three core macro-trends are shaping the future demand trajectory of CAS 123-00-2:
Regulatory tightening on volatile organic compounds (VOCs) in Europe, North America, and East Asia is forcing coating manufacturers to replace legacy solvents with high-solids or 100% solids epoxy systems. N-(3-Aminopropyl)morpholine’s combination of low vapor pressure and low viscosity allows it to act as a reactive diluent while curing effectively, eliminating volatile solvent requirements.
As carbon capture, utilization, and storage (CCUS) projects scale globally to combat industrial emissions, specialized morpholine-derived amines like CAS 123-00-2 are gaining rapid market share. Their superior thermal stability prevents degradation during solvent regeneration cycles, reducing amine loss and operational expenditure in industrial scrubbers.
JIMPOCHEM is pioneering continuous green chemistry initiatives in Shandong, optimizing catalytic efficiency to reduce reaction energy consumption by 18%. Our R&D teams are actively evaluating bio-derived acrylonitrile feedstocks to offer carbon-neutral certified CAS 123-00-2 batches by 2026.
JIMPOCHEM
