Explore our flagship product inventory engineered for high-precision chemical synthesis, pharmaceutical manufacturing, and specialty cosmetics. Delivered direct from China's leading chemical industrial base.
2-Benzenedicarboxaldehyde, widely recognized in commercial and scientific sectors as o-Phthalaldehyde (OPA, CAS 643-79-8), stands as an indispensable aromatic dialdehyde compound containing two aldehyde groups adjacent to each other on a benzene ring. Due to its unique structural reactivity, high efficacy as a high-level disinfectant (HLD), and versatility as an intermediate in bio-analytical assay chemistry and pharmaceutical synthesis, 2-Benzenedicarboxaldehyde has become a vital strategic material across global medical, analytical, and specialty chemical markets.
As a premiere China 2-Benzenedicarboxaldehyde supplier & factory operator, JIMPOCHEM CO., LTD delivers technical-grade and pharmaceutical-grade 2-Benzenedicarboxaldehyde exceeding 99.0% and 99.5% purity (determined via HPLC). Our state-of-the-art manufacturing plant in Shandong, China, utilizes closed-loop catalytic oxidation protocols to ensure minimal trace aldehyde impurities, batch-to-batch consistency, and compliance with rigorous international quality frameworks.
| Property / Parameter | Technical Specification Value | Testing Standard / Analytical Method |
|---|---|---|
| Chemical IUPAC Name | 1,2-Benzenedicarboxaldehyde / 2-Benzenedicarboxaldehyde | IUPAC Standard Nomenclature |
| Common Synonyms | o-Phthalaldehyde, Phthalaldehyde, OPA, Ortho-phthalaldehyde | CAS Registry Index |
| CAS Registry Number | 643-79-8 | CAS Verification |
| EC / EINECS Number | 211-402-2 | EU REACH Chemical Index |
| Molecular Formula / Weight | C8H6O2 / 134.13 g/mol | Mass Spectrometry (MS) |
| Purity / Assay (HPLC) | ≥ 99.0% (Technical Grade) | ≥ 99.5% (High Purity / Pharma Grade) | High-Performance Liquid Chromatography |
| Physical Appearance | Yellowish to pale yellow crystalline powder / crystals | Visual / Colorimetric Inspection |
| Melting Point Range | 55.0 °C – 58.0 °C | Capillary Melting Point Apparatus |
| Solubility Profile | Soluble in water, ethanol, ether, and organic solvents | Gravimetric Solubility Test (20°C) |
| Loss on Drying | ≤ 0.5% | Vacuum Drying at 40°C |
| Residue on Ignition | ≤ 0.1% | Thermogravimetric Furnace Analysis |
The commercial synthesis of 2-Benzenedicarboxaldehyde has evolved from classic halogenated hydrocarbon hydrolysis to ultra-modern, eco-friendly catalytic oxidation processes. Industrial buyers demand non-toxic impurity profiles, minimal residual heavy metals, and reduced carbon intensity. Below is an in-depth breakdown of current synthesis routes and future technology trajectories implemented across leading Chinese factories:
Utilizing a gas-phase fluidized bed reactor with V2O5-TiO2 catalysts, o-Xylene undergoes partial oxidation under controlled temperature conditions (340°C–380°C). While highly scalable, this route requires ultra-precise thermal management to prevent over-oxidation into phthalic anhydride.
Side-chain chlorination of o-Xylene yields α,α,α',α'-tetrachloro-o-xylene, followed by acid hydrolysis. Although cost-effective, this pathway generates halogenated waste streams requiring intensive environmental scrubbing. JIMPOCHEM has phased out this process in favor of zero-chlorine alternatives.
The flagship innovation adopted in JIMPOCHEM’s modern facilities. O-Xylene or o-phthaldialcohol undergoes liquid-phase catalytic oxidation with green oxidants (such as H2O2 or molecular O2) inside continuous microchannel reactors, achieving >99.5% purity with zero organochlorine byproducts.
Current R&D centers on electrochemical catalytic synthesis and enzymatic oxidation systems. These advanced techniques aim to lower energy consumption by 40%, eliminate toxic organic solvents entirely, and produce ultra-pure 2-Benzenedicarboxaldehyde tailored for biomedical micro-assays.
The versatile reactivity of the dual aldehyde functionalities makes 2-Benzenedicarboxaldehyde a non-replaceable ingredient in several key global sectors:
In healthcare facilities worldwide, 0.55% buffered o-Phthalaldehyde solutions have largely superseded glutaraldehyde as the gold-standard High-Level Disinfectant (HLD) for heat-sensitive medical instruments, flexible endoscopes, and surgical equipment.
In biochemical research, food analysis, and diagnostic testing, 2-Benzenedicarboxaldehyde serves as a rapid derivatizing reagent for primary amines and amino acids.
As a structural building block, 2-Benzenedicarboxaldehyde undergoes condensations, cyclizations, and reductive aminations to form complex heterocycles.
The bifunctional nature of 2-Benzenedicarboxaldehyde allows it to act as an efficient crosslinking agent for natural and synthetic polymers.
Global chemical buyers facing supply chain disruptions, soaring logistics costs, and strict environmental audits turn to China’s robust industrial ecosystem for guaranteed supply security. JIMPOCHEM CO., LTD exemplifies the top tier of Chinese fine chemical manufacturing:
Located within the Jinan Chemical Industry Park, JIMPOCHEM benefits from upstream raw material integration (direct pipeline access to aromatic hydrocarbons), reducing raw material procurement volatility and ensuring continuous production uptime.
Equipped with multi-ton automated batch reactors and continuous distillation units, our facility handles small R&D sample requests up to multi-hundred MT commercial orders with consistent quality tolerances.
Adhering to China's national dual-carbon goals, our plant integrates MVR (Mechanical Vapor Recompression) wastewater treatment, RTO (Regenerative Thermal Oxidizer) off-gas incineration, and complete energy recovery systems.
The global market demand for 2-Benzenedicarboxaldehyde is experiencing sustained compound annual growth rates (CAGR > 6.2%), driven primarily by expanding healthcare infrastructure in emerging economies, increasing adoption of automated endoscope reprocessors (AER), and surging demand for high-purity analytical assay reagents.
Strict FDA infection control protocols drive steady demand for high-purity OPA formulations. Major hospital networks prioritize standardized, fast-acting HLD solutions with low toxicological footprints.
Strong emphasis on REACH compliance, SVHC avoidance, and eco-friendly manufacturing pathways. Importers favor Chinese suppliers with full REACH dossier support and ISO 14001 certification.
Rapid growth in pharmaceutical synthesis hubs across India, Southeast Asia, and South America. High demand for cost-competitive technical grade 2-Benzenedicarboxaldehyde as API building blocks.
At JIMPOCHEM, "Quality is the Lifeline of the Enterprise." We adhere strictly to Google’s E-E-A-T (Experience, Expertise, Authoritativeness, Trustworthiness) standards by providing transparent batch documentation, analytical trace reports, and comprehensive regulatory assistance.
Every shipment comes with a unique Lot Number linked to raw material source logs, reaction parameters, GC-MS / HPLC spectra, and QC sign-offs. Customers can audit batch records on demand.
We provide full documentation required for international market entry, including SDS/MSDS (GHS compliant), Certificate of Analysis (COA), REACH Registration Support, ISO 9001:2015, and ISO 14001:2015 certificates.
2-Benzenedicarboxaldehyde is packaged in UN-approved 25kg fiber drums with double PE liner bags, or custom 100g/1kg light-protected aluminum foil pouches for laboratory users, ensuring zero moisture absorption or degradation during transoceanic shipping.
JIMPOCHEM CO., LTD was established in 2010 and is headquartered in the Chemical Industry Park of Jinan City, Shandong Province. Spanning an expansive area of over 500 acres, the company is a professional chemical raw material manufacturer integrating research and development, large-scale production, global sales, and dedicated technical services. Its core focus spans high-end fine chemicals, pharmaceutical intermediates, and high-performance cosmetic ingredients.
Our core team comprises veteran chemists and chemical engineers with over 10 years of industrial experience. Beyond high-purity chemical supply, we offer end-to-end solutions in product synthesis development, custom formulation optimization, and international supply chain risk management. Serving over 5,000 corporate clients across 200+ countries, JIMPOCHEM has become a designated, long-term strategic partner for worldwide chemical buyers.
Explore additional complementary specialty chemical products manufactured and distributed by JIMPOCHEM for global healthcare, daily chemical, and advanced material industries.
JIMPOCHEM