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Octylphenoxypolyethoxyethanol (commonly known by trade names such as Triton X-100, Octoxynol-9, or Polyethylene glycol tert-octylphenyl ether) is a nonionic surfactant featuring a hydrophilic polyethylene oxide chain and a lipophilic hydrocarbon group (a 4-(1,1,3,3-tetramethylbutyl)-phenyl group). As a cornerstone compound in modern chemical manufacturing, diagnostic assay design, industrial emulsification, and biochemical research, selecting a verified Octylphenoxypolyethoxyethanol supplier & factory is vital for maintaining batch-to-batch consistency and regulatory compliance.
At JIMPOCHEM CO., LTD, we manufacture high-purity Octylphenoxypolyethoxyethanol under strict automated process controls, ensuring an optimized Hydrophilic-Lipophilic Balance (HLB) value of approximately 13.5 and low peroxide indices essential for sensitive cell lysis, virus inactivation, and high-performance latex dispersion formulations.
Octylphenoxypolyethoxyethanol possesses a average molecular weight ranging from 625 to 647 g/mol depending on the ethoxylation degree (n ≈ 9-10). Its mild non-denaturing detergent profile makes it uniquely qualified to solubilize integral membrane proteins while maintaining catalytic activity in biochemical reagents.
| Parameter | Standard Technical Specification | Diagnostic / Reagent Grade Specification |
|---|---|---|
| CAS Registry Number | 9002-93-1 | 9002-93-1 |
| Appearance | Clear, light yellow viscous liquid | Colorless to pale yellow transparent liquid |
| Active Content (%) | ≥ 99.0% | ≥ 99.5% (HPLC purity) |
| HLB Value | 13.4 – 13.6 | 13.5 |
| Cloud Point (1% in H₂O) | 63°C – 67°C | 64°C – 66°C |
| pH (5% Aqueous Solution) | 6.0 – 8.0 | 6.5 – 7.5 |
| Free Hydroperoxides | ≤ 50 ppm | ≤ 10 ppm (Ultra-Low Peroxide Grade) |
| Water Content (Karl Fischer) | ≤ 0.5% | ≤ 0.2% |
Ensuring precise molecular oligomer distribution and ultra-pure ethoxylation through digitized reactor controls.
Synthesis begins with controlled alkylation of phenol to produce 4-tert-octylphenol, followed by catalytic ethoxylation using ethylene oxide (EO). Our pressurized batch reactors utilize narrow-range ethoxylation catalysts to yield a highly uniform Gaussian distribution of polyoxyethylene chains.
Unreacted ethylene oxide, residual octylphenol monomers, and volatile side-products (such as 1,4-dioxane) are systematically extracted via high-vacuum falling film evaporation. This process reduces trace impurities to sub-ppm levels, satisfying stringent biochemical purity standards.
Looking toward the future, JIMPOCHEM is pioneering eco-friendly bio-based surfactants. We offer consultation and customized synthesis of alcohol ethoxylates (AEOs) and alkyl polyglucosides (APGs) as functional substitutes for regulatory-restricted OPE applications under REACH Annex XIV.
From diagnostic immunoassay kits in North America to heavy-duty industrial degreasing across Europe and Asia, Octylphenoxypolyethoxyethanol serves as a high-performance chemical standard.
In biopharmaceutical cell culture and In-Vitro Diagnostics (IVD), Octylphenoxypolyethoxyethanol acts as a reliable non-denaturing detergent. It solubilizes lipid membranes without breaking nucleic acid bonds, proving indispensable in lysis buffers (RIPA buffers), ELISA washing protocols, and viral inactivation steps during biological drug manufacturing.
In latex paint, architectural coatings, and acrylic emulsion production, it functions as a primary nonionic emulsifier. It enhances mechanical stability, freeze-thaw resistance, and pigment wetting efficiency, preventing phase separation during storage and application.
During semiconductor wafer processing and printed circuit board (PCB) fabrication, low-metal-content grades of Octylphenoxypolyethoxyethanol act as wetting agents, ensuring uniform acid etchant contact across hydrophobic sub-micron silicon structures.
Formulated into liquid pesticide, herbicide, and fungicide concentrates, Octylphenoxypolyethoxyethanol drastically reduces droplet surface tension, promoting uniform foliage coverage and leaf-cuticle penetration even under high rainfall conditions.
Utilized in heavy-duty industrial degreasers and textile scouring agents, its cloud point properties allow effective displacement of synthetic greases, mineral oils, and particulate dirt from metallic or cotton surfaces.
JIMPOCHEM works alongside global brand managers to supply custom-blended concentration ratios, modified HLB blends, and private-label packaging to streamline direct factory integration.
Navigating international regulatory frameworks is critical for industrial buyers purchasing Octylphenoxypolyethoxyethanol (CAS 9002-93-1). Regulatory bodies including the European Chemicals Agency (ECHA) under REACH and the United States Environmental Protection Agency (EPA) closely monitor nonylphenol and octylphenol ethoxylates due to aquatic degradation concerns.
In the European Union, 4-(1,1,3,3-tetramethylbutyl)phenol, ethoxylated is listed on REACH Annex XIV (Authorisation List). Industrial buyers must ensure compliance through specific authorized use cases (e.g., in-vitro diagnostics reagent production, medical equipment washing, and pharmaceutical production) or transition to REACH-compliant alternative nonionic surfactants supplied by JIMPOCHEM.
In North America, Octylphenoxypolyethoxyethanol remains registered on the TSCA Inventory. JIMPOCHEM provides certified chemical safety documentation (GHS SDS), facilitating smooth customs clearance and regulatory reporting for North American manufacturing partners.
Every shipment from our factory is accompanied by a batch-specific Certificate of Analysis (CoA) detailing HPLC purity, moisture content, hydroxyl value, and residual VOC levels. Our product barcode tracking system enables complete upstream traceability from raw material storage to your warehouse floor.
JIMPOCHEM CO., LTD operates as a premier chemical manufacturer based in Shandong, China. We combine vast manufacturing scale with agile supply chain management.
Established in 2010 and strategically located within the Jinan Chemical Industry Park, Shandong Province, JIMPOCHEM's manufacturing site spans over 500 acres. Equipped with fully automated Distributed Control Systems (DCS) and digital monitoring, our chemical synthesis lines deliver high-capacity throughput while guaranteeing stringent operational safety and environmental sustainability.
We leverage stable raw material supply routes directly linked to major petroleum refineries, isolating our clients from global chemical spot price volatility and ensuring uninterrupted production cycles.




From formulation refinement to green chemistry transformations, we offer one-on-one technical service tailored to your industry.
Our facility operates under strict ISO 9001 quality management and ISO 14001 environmental safety frameworks. In-house testing utilizes HPLC, Gas Chromatography (GC), ICP-MS for metal trace detection, and Karl Fischer titrators to verify every batch.
We support standard and customized B2B shipping specifications: 25kg plastic drums, 200kg steel/HDPE drums, and 1000kg IBC totes. We handle full hazard classification logistics, sea freight containerization, and expedited air transport for diagnostic kit manufacturers.
Our core R&D team consists of chemical engineers with over a decade of hands-on synthesis experience. We offer one-on-one technical consultation to optimize your product formulas, lower surfactant loading requirements, and reduce total cost of ownership.






Answers to critical questions regarding Octylphenoxypolyethoxyethanol procurement, specifications, testing, and shipping.
Triton X-100 is a registered trademark brand name for Octylphenoxypolyethoxyethanol (CAS 9002-93-1). Chemical identity, structural formula, molecular weight distribution, and performance are identical. JIMPOCHEM manufactures high-purity Octylphenoxypolyethoxyethanol as a direct equivalent for Triton X-100 in diagnostic, research, and industrial applications.
Yes. For sensitive enzyme assays, monoclonal antibody processing, and cell lysis protocols where hydroperoxides interfere with target proteins, JIMPOCHEM offers specialized ultra-pure, low-peroxide grades (<10 ppm peroxide content) sealed under argon atmosphere.
Because 4-tert-octylphenol ethoxylates are subject to REACH Annex XIV authorizations, we assist European customers by providing compliant technical documentation for exempted uses (such as in-vitro diagnostics or scientific R&D). Additionally, we offer drop-in alternative nonionic surfactants (e.g., eco-friendly alcohol ethoxylates) that do not require REACH authorization.
Our standard packaging includes 25kg pails, 200kg drums, and 1000kg IBC totes. Minimum order quantity starts at 200kg for standard stock items. Lead time for international ocean freight typically ranges between 7 to 14 days post-order verification.
Absolutely. We provide qualified industrial buyers and laboratory research teams with sample quantities (ranging from 100g to 1kg) complete with batch Certificates of Analysis (CoA) and Safety Data Sheets (SDS) for preliminary testing.
Octylphenoxypolyethoxyethanol should be stored in tightly sealed original containers in a cool, dry, well-ventilated area away from direct sunlight and strong oxidizing agents. Under recommended storage conditions (15°C – 25°C), shelf-life is guaranteed for 24 months from the date of manufacture.
With an HLB value of 13.5, it serves as an effective secondary emulsifier alongside anionic surfactants (such as SDS or linear alkylbenzene sulfonate). It provides steric stabilization to polymer latex particles, preventing coagulation during high-shear agitation or temperature fluctuations.
JIMPOCHEM brings 16 years of chemical manufacturing expertise, a 500+ acre modern production infrastructure, ISO certified quality control, transparent factory-direct pricing, and localized technical support for over 5,000 corporate clients globally.
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