Direct factory supply of high-purity functional chemicals and active pharmaceutical intermediates.
Comprehensive Scientific Evaluation, Antimicrobial Kinetics, & Manufacturing Specifications
Benzethonium Chloride (also known as Hyamine 1622) is a synthetic quaternary ammonium salt exhibiting exceptional cationic surfactant and microbicidal properties. Its chemical architecture consists of a hydrophobic lipophilic tail and a positively charged quaternary nitrogen head.
Benzethonium Chloride exerts broad-spectrum bactericidal, microbicidal, and fungicidal action through electrostatic and hydrophobic interactions with pathogenic cellular envelopes:
JIMPOCHEM produces Benzethonium Chloride adhering to rigorous pharmaceutical monograph requirements (USP / EP / JP / ChP). Analytical validation includes full LC-MS, FT-IR, and heavy metal testing.
| Parameter / Test Item | USP Pharmaceutical Grade | Cosmetic Preservative Grade | Industrial Disinfectant Grade |
|---|---|---|---|
| Assay (Drying Basis) | 99.0% – 101.0% | 98.5% – 101.0% | ≥ 97.0% |
| Appearance | White Crystalline Powder | White to Off-White Powder | White/Light Yellowish Powder |
| Melting Point Range | 158.0°C – 164.0°C | 156.0°C – 164.0°C | 154.0°C – 162.0°C |
| pH (1% aqueous solution) | 5.5 – 6.5 | 5.0 – 7.0 | 5.0 – 7.5 |
| Residue on Ignition | ≤ 0.1% | ≤ 0.2% | ≤ 0.5% |
| Heavy Metals (Pb, As) | ≤ 10 ppm | ≤ 20 ppm | ≤ 50 ppm |
| Residual Solvents (ICH Q3C) | Meets ICH Limits | Compliant | N/A |
Engineered for high efficacy across pharmaceutical, cosmetic, food safety, and industrial water treatment sectors.
Benzethonium chloride serves as an active pharmaceutical ingredient (API) in OTC topical anti-infectives, first-aid wound sprays, skin cleansers, and ophthalmic solutions. It offers superior residual activity on human skin without causing severe tissue irritation at recommended dosage levels (typically 0.1% to 0.2%).
Used extensively as a broad-spectrum preservative in leave-on and rinse-off products, including wet wipes, hand sanitizers, deodorants, anti-dandruff shampoos, and facial lotions. Protects formulations against Gram-positive, Gram-negative bacteria, mold, and yeast contamination.
Formulated into hospital-grade disinfectant sprays and floor cleaners. Demonstrates rapid kill rates against resistant strains including MRSA and Pseudomonas aeruginosa. Compatible with non-ionic surfactants for enhanced cleaning power.
Applied in equipment sanitization solutions across dairy plants, breweries, and food packing facilities. Odorless and non-corrosive to stainless steel equipment when utilized within standard operational concentrations.
Prevents bio-fouling and algal blooms in recirculating cooling towers, paper manufacturing systems, and industrial wastewater installations, ensuring optimal thermodynamic heat transfer.
Utilized in livestock housing disinfection, udder washes for mastitis control in dairy farming, and water microbial control in commercial aquaculture hatcheries.
Integrating R&D, Automated Synthesis, Stringent QA, and Seamless Global Delivery
Located in the Chemical Industry Park of Jinan City, Shandong Province, our state-of-the-art facility features automated batch reaction vessels and crystal purification lines. Direct raw material access guarantees uninterrupted production and stable bulk pricing.
Our operations hold ISO9001 quality management system, ISO14001 environmental system certifications, full REACH registrations for Europe, and standard FDA DMF support. We welcome third-party audits (SGS, Intertek, Bureau Veritas).
We offer flexible packaging solutions—from 25kg fiber drums to multi-ton ISO tanks. Customized liquid solutions (10%, 20%, 50% aqueous solutions) and powder micronization available upon demand with vendor-managed inventory options.
Market Shifts Shaping Cationic Antimicrobial Procurement in 2025 and Beyond
With increasing global restrictions on traditional preservatives like Triclosan, Triclocarban, and parabens due to endocrine disruption concerns, multi-national personal care brands are transitioning to quaternary ammonium compounds. Benzethonium Chloride offers higher efficacy at lower concentration thresholds with an established safety profile.
In clinical and cleanroom hygiene, standard alcohol-based sanitizers lack residual killing capacity once evaporated. Benzethonium Chloride deposits a persistent antimicrobial film that retains microbicidal activity for hours, driving strong adoption in healthcare and high-traffic institutional settings.
Sustainable manufacturing practices are paramount. JIMPOCHEM’s clean technology synth-pathway reduces organic effluent waste by 40% and eliminates heavy metal catalysts during alkylation, meeting international ESG standards for eco-friendly chemical sourcing.
Global pharmaceutical and FMCG conglomerates are actively establishing strategic partnerships with tier-1 Chinese manufacturers to diversify supply lines, mitigating geopolitical and logistical bottlenecks through long-term annual volume contracting.
Explore our 500+ acre state-of-the-art production base and quality control laboratories.
Technical and Commercial Clarifications for Benzethonium Chloride Purchasing
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