China Octanoic Acid Sodium Salt Manufacturer & Factory

High-Purity Sodium Caprylate (CAS 1984-06-1) for Pharmaceutical Bioseparation, Personal Care Formulations, and Industrial Fine Synthetics

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Technical Whitepaper: Octanoic Acid Sodium Salt (Sodium Caprylate)

Comprehensive analytical chemistry profile, structural characteristics, and regulatory parameters for CAS 1984-06-1.

Chemical Identity & Structure

Octanoic acid sodium salt, commercially designated as Sodium Caprylate (CAS 1984-06-1; EC Number 217-850-5), is the sodium salt of saturated medium-chain C8 fatty acid (caprylic acid). Possessing the molecular formula C8H15NaO2 and a molecular weight of 166.19 g/mol, this amphiphilic compound exhibits unique thermodynamic stability, surface tension lowering capabilities, and protein stabilization properties.

Key Molecular Data:

IUPAC Name: Sodium octanoate
Synonyms: Caprylic acid sodium salt, Sodium caprylate
InChIKey: KWGJAOGEAYVNAV-UHFFFAOYSA-M
Solubility: Soluble in water (approx. 100 mg/mL at 20°C), sparingly soluble in alcohol.

Industrial & Bio-Pharmaceutical Utility

As a leading China Octanoic acid sodium salt manufacturer, JIMPOCHEM produces ultra-pure grades engineered specifically to meet strict pharmacopeial monographs (EP, USP, ChP). In biomanufacturing, it serves as a critical structural stabilizer for Human Serum Albumin (HSA) pasteurization and biological plasma fractionation processes, preventing thermal denaturation of proteins at 60°C. Additionally, its amphiphilic structure enables widespread application as a micro-ecological preservative booster, surfactant co-emulsifier, and intermediate in advanced organic synthesis.

Comprehensive Specifications Table

Specification Parameter Pharma Grade (Pasteurization Grade) Cosmetic / Personal Care Grade Industrial / Fine Synthesis Grade
Appearance White crystalline powder White powder to off-white granule White or light yellowish powder
Assay (Dry Basis) ≥ 99.0% - 101.0% ≥ 98.5% ≥ 98.0%
Bacterial Endotoxins < 0.10 EU/mg (Ultra-low) N/A N/A
Heavy Metals (as Pb) ≤ 5 ppm ≤ 10 ppm ≤ 20 ppm
Loss on Drying ≤ 1.0% ≤ 2.0% ≤ 3.0%
pH Value (5% aqueous sol.) 8.0 – 10.5 8.0 – 10.5 7.5 – 11.0
Clarity of Solution Clear and colorless (5% in H2O) Slightly opalescent acceptable Passes test

Manufacturing Route & Advanced Quality Control

High-yield saponification, fractional crystallization, and multi-stage endotoxin reduction engineering.

1. High-Purity Saponification

Our direct stoichiometric reaction between ultra-refined C8 octanoic acid (purity >99.5%) and food-grade sodium hydroxide (NaOH) under controlled thermal conditions eliminates unreacted lipid residues and volatile short-chain fatty acids, guaranteeing exceptionally low odor profiles.

2. Fractional Crystallization

Utilizing proprietary multi-stage vacuum crystallization and ethanol-water solvent refinement, JIMPOCHEM removes trace inorganic salts and structural isomers, yielding macro-crystalline particles with optimal dissolution kinetic curves and superior bulk density consistency.

3. Pyrogen Depyrogenation

For injectable and biopharmaceutical plasma fractionation grades, process fluids pass through automated ultrafiltration membrane systems (10 kDa cutoff) combined with high-temperature sterile spray drying to enforce strict pyrogen-free conditions (<0.10 EU/mg endotoxin levels).

Global Sector Solutions & Strategic Applications

How top international enterprises incorporate our Sodium Caprylate in high-tech industrial sectors.

Biopharmaceutical & Blood Plasma Fractionation

During the Cohn fractionation process for Human Serum Albumin (HSA), heat treatment at 60°C for 10 hours is mandatory to deactivate blood-borne pathogens. Octanoic acid sodium salt selectively binds to hydrophobic domains on albumin molecules, increasing thermal stability without precipitating the protein. Furthermore, it acts as a selective precipitation agent and stabilizing buffer in serum-free cell culture media formulations for CHO cell lines.

Personal Care & Micro-Ecological Cosmetics

In modern cosmetic chemistry, Sodium Caprylate functions as a skin-friendly antimicrobial booster and mild surfactant adjuvant. Its medium-chain carbon backbone disrupts lipid cell membranes of unwanted micro-organisms (such as Malassezia species), enhancing the efficacy of broad-spectrum green preservatives while reducing required dosages of synthetic parabens or phenoxyethanol.

Specialty Polymers, Catalysts & Lubricants

In synthetic resin production, Sodium Caprylate acts as an effective emulsifier for emulsion polymerization processes, controlling latex particle size distributions. It also finds application in metalworking fluids and synthetic lubricants as a bio-degradable rust inhibitor and corrosion control agent on ferrous surfaces under mild alkaline conditions.

Food Preservation & Animal Nutrition

As a short-to-medium chain fatty acid salt (MCFA), it displays strong pH-dependent antifungal and antibacterial properties against foodborne pathogens (e.g., Salmonella enterica, E. coli). When added to animal feed premixes, it supports gut health optimization in swine and poultry by regulating intestinal microbiota balance.

About JIMPOCHEM CO., LTD.

Designated chemical service provider bridging state-of-the-art Chinese manufacturing with global procurement networks.

16+
Years Industry Expertise
500+
Acres Industrial Base
200+
Countries & Regions Served
5000+
Global Corporate Partners

Corporate Overview & Manufacturing Infrastructure

JIMPOCHEM CO., LTD was established in 2010 and is headquartered in the Chemical Industry Park of Jinan City, Shandong Province. The company covers an area of over 500 acres and is a professional chemical raw material manufacturer that integrates research and development, production, sales, and technical services. Its core focus is on high-end fine chemicals and cosmetic raw materials. We have obtained multiple product-related certifications, including ISO quality system certification and environmental management system certification, and are committed to providing high-quality chemical products and one-stop procurement service solutions to global customers.

Our core team comprises experts with over 10 years of experience in the chemical industry. This enables us not only to provide professional products but also to offer solutions in product development, formula optimization, and supply chain management, meeting the personalized needs of diverse clients. We provide high-quality products and services, and our products are exported to over 200 countries and regions in Europe, America, Southeast Asia, the Middle East, and Oceania, serving more than 5,000 international companies. We have also established long-term strategic partnerships with many internationally renowned chemical companies, becoming a trusted "designated chemical service provider" for numerous clients.

Core Competitive Advantages

1. Supply Chain and Production Capacity

Leveraging years of industry experience, we have established stable raw material procurement channels and partnered with top global chemical raw material suppliers, ensuring stable raw material quality and ample supply. Our modern production base employs an intelligent control system to automate and digitally manage the production process, balancing large-scale production with flexible customization needs.

2. Rigorous Quality Control Framework

Adhering to the philosophy that "quality is the lifeline of an enterprise," the company has established a comprehensive quality control system. From raw material warehousing inspection to real-time process monitoring and full-item testing of finished products before shipment, every step adheres to strict standards. A complete batch traceability system connects raw material lots to testing data and shipping logs.

3. Green & Environmental Leadership

In response to the global "dual-carbon" strategy, we focus on the research, development, and production of green chemical products. By optimizing wastewater, waste gas, and waste residue treatment systems, we achieve compliant pollutant emissions and resource recycling, supporting downstream customers in their green production transformation.

Factory Tour & Operational Excellence

Compliance Standards, Packaging & Freight Engineering

Ensuring regulatory conformity, chemical stability, and safe transoceanic transit.

Regulatory Declarations

Our Octanoic acid sodium salt (CAS 1984-06-1) fully complies with EU REACH registration specifications, US FDA DMF filings, Kosher, Halal, and ISO 9001/14001 quality audits. Detailed Safety Data Sheets (SDS) in compliance with GHS standards are included with every shipment.

Standard Export Packaging

Supplied in 25 kg net weight fiber drums lined with double-layer heavy-duty polyethylene inner bags to prevent moisture absorption. Customized bulk packaging options including 500 kg super-sacks or aluminum-foil moisture barrier packaging are available upon buyer request.

Global Logistics Handling

Non-hazardous for sea, air, and land transport under international IMDG/IATA transport codes. Stocked in temperature and humidity-monitored bonded warehouses to support rapid emergency dispatch to ports in Europe, North America, Middle East, and Southeast Asia.

Frequently Asked Questions (Technical Q&A)

In-depth technical answers addressing procurement, application, and chemistry questions.

What is Octanoic Acid Sodium Salt and what is its primary chemical function?
Octanoic acid sodium salt (CAS 1984-06-1), also widely known as Sodium Caprylate, is the sodium salt of medium-chain C8 caprylic acid. Functionally, it serves as an amphiphilic surfactant, protein stabilizing agent (specifically for Human Serum Albumin during heat treatment), selective microbial growth inhibitor, and intermediate in advanced chemical syntheses.
Why is Sodium Caprylate essential in Human Serum Albumin (HSA) pasteurization?
During the thermal inactivation phase of plasma-derived albumin manufacturing (60°C for 10 hours), protein structures risk thermal denaturation and irreversible aggregation. Sodium caprylate binds tightly to the hydrophobic pockets of albumin, significantly enhancing its conformational heat stability without interfering with downstream therapeutic efficacy or inducing protein precipitation.
What analytical methods are utilized for quality verification of Sodium Caprylate?
JIMPOCHEM utilizes high-performance liquid chromatography (HPLC), gas chromatography (GC) for fatty acid profile identification, potentiometric titration for strict assay determination (99.0%–101.0%), inductively coupled plasma mass spectrometry (ICP-MS) for heavy metal trace analysis, and Chromogenic LAL assays for bacterial endotoxin testing.
How does Sodium Caprylate function as a preservative booster in cosmetics?
The lipophilic C8 hydrocarbon chain inserts into the phospholipid bilayer of bacterial and fungal cell membranes, altering membrane permeability and membrane potential. This synergistic mechanism allows formulators to reduce concentrations of conventional antimicrobial preservatives while maintaining broad-spectrum preservation efficacy.
Can JIMPOCHEM provide custom particle sizing or endotoxin-controlled grades?
Yes, as a specialized China Octanoic acid sodium salt manufacturer, we offer custom processing options including micronized powders, granular shapes, and specialized ultra-low endotoxin pharmaceutical grades (<0.10 EU/mg) packaged under cGMP-compliant cleanroom conditions.
What is the shelf life and recommended storage conditions for bulk purchases?
When stored in original sealed containers in a cool, dry, well-ventilated warehouse away from strong oxidizers and direct sunlight, Octanoic acid sodium salt maintains a shelf life of 24 months from the manufacturing date.

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