China 3-Morpholinopropylamine Manufacturer & High-Purity Chemical Products

Global Chemical Solutions Leader | CAS 123-00-2 Industrial Whitepaper & Supply Chain Portal for Advanced Polymers, Gas Treatment, and Fine Chemical Intermediates

ISO 9001:2015 & ISO 14001 Certified Purity ≥ 99.5% (GC Grade) 10,000 MT/Year Capacity

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3-Morpholinopropylamine (CAS 123-00-2): Technical Overview & Structural Profile

3-Morpholinopropylamine (commonly designated as N-(3-Aminopropyl)morpholine, 4-(3-Aminopropyl)morpholine, or APM / PCPA) is a vital heterocycle-containing primary amine compound characterized by the presence of both a tertiary amine ring (morpholine ring) and a primary aliphatic amine terminal group. This dual-functionality grants exceptional catalytic, curing, and chelating behavior in advanced organic synthesis, polymer engineering, and gas sweetening operations.

Chemical Identity & Nomenclature

  • IUPAC Name: 3-(Morpholin-4-yl)propan-1-amine
  • CAS Registry Number: 123-00-2
  • EINECS / EC Number: 204-590-2
  • Molecular Formula: C7H16N2O
  • Molecular Weight: 144.22 g/mol
  • Synonyms: 4-Morpholinepropanamine; N-(3-Aminopropyl)morpholine; APM; 3-Morpholin-4-ylpropan-1-amine
  • InChI Key: YNAVYTYTYRGUBO-UHFFFAOYSA-N

Core Performance Attributes

The structural synergy between the ether linkage in the morpholine oxygen and the basic nitrogen atoms imparts exceptional chemical characteristics:

  • Bifunctional Reactivity: Primary amine reacts smoothly with epoxy rings, carboxylic acids, and isocyanates, while the tertiary amine acts as a latent accelerator.
  • High Water Miscibility & Solvent Compatibility: Completely soluble in water, ethanol, ether, and aromatic hydrocarbons.
  • Thermal Stability: High boiling point (224°C) minimizes volatile loss during thermal processing of epoxy matrices and polyurethane curing.

Industrial Standard Specifications & Quality Control parameters

At JIMPOCHEM CO., LTD, each batch of 3-Morpholinopropylamine undergoes rigorous Gas Chromatography (GC-FID/MS) testing, Karl Fischer titration, and spectrographic color analysis to ensure full compliance with strict global standards.

Inspection Item Guaranteed Standard (Industrial Grade) High-Purity Grade (Fine Chemical) Test Method
Appearance Clear, colorless to light yellow liquid Clear, colorless liquid Visual Inspection
Purity (GC Assay) ≥ 99.0% ≥ 99.5% Gas Chromatography (GC-FID)
Water Content (Moisture) ≤ 0.30% ≤ 0.10% ASTM E203 (Karl Fischer)
Color Scale (APHA / Hazen) ≤ 50 Pt-Co ≤ 20 Pt-Co ASTM D1209 Standard
Density (20°C) 0.982 – 0.988 g/cm³ 0.984 – 0.986 g/cm³ Pycnometer / Digital Density Meter
Refractive Index (n20/D) 1.4740 – 1.4780 1.4755 – 1.4765 Refractometer
Primary Amine Content ≥ 98.5% ≥ 99.2% Potentiometric Titration
Morpholine Impurity ≤ 0.20% ≤ 0.05% GC Impurity Profiling

Advanced Chemical Synthesis Route & Technology Roadmap

JIMPOCHEM’s modern synthesis pathway leverages catalytic Michael addition followed by continuous fixed-bed high-pressure hydrogenation, establishing an efficient, green, and zero-discharge production matrix.

1. Cyanoethylation Step

Morpholine undergoes a controlled nucleophilic addition reaction with acrylonitrile in the presence of basic catalysts. This Michael addition yields 4-morpholinepropanenitrile (3-morpholinopropionitrile) under continuous thermal control to eliminate byproduct polymerization.

2. Catalytic Hydrogenation

The resulting nitrile intermediate is pumped into a high-pressure continuous catalytic fixed-bed reactor filled with proprietary modified Raney-Cobalt/Nickel catalysts. Hydrogenation under anhydrous ammonia gas suppresses secondary amine formation, ensuring >99.5% selectivity.

3. Precision Vacuum Distillation

Crude 3-morpholinopropylamine undergoes multi-stage vacuum fractionation columns under high vacuum (5-10 mbar). Low-boiling light ends and heavy residues are removed, yielding clear, high-purity product with ultra-low moisture and low color index.

Macro Industry Solutions & Downstream Applications

As a designated chemical provider serving over 5,000 global partners across 200+ countries, JIMPOCHEM’s 3-Morpholinopropylamine is engineered for multi-industry versatility:

1. Epoxy Resin Curing Agents & Accelerators

In epoxy resin systems, 3-Morpholinopropylamine functions both as a curing agent and a latent co-catalyst. The primary amine initiates rapid crosslinking with bisphenol-A epoxy resins, while the tertiary morpholine nitrogen significantly lowers reaction activation energy.

  • Key Benefits: Excellent thermal distortion temperature (HDT), high mechanical strength, rapid room-temperature curing capability.
  • Applications: Structural adhesives, heavy-duty anti-corrosion marine coatings, electronic encapsulation resins.

2. Polyurethane Foams & Elastomers (PU Catalysts)

The tertiary amine ring structure acts as a tertiary amine blowing and gelling catalyst in rigid and flexible polyurethane foam formulations.

  • Key Benefits: Promotes balanced urethane (polyol-isocyanate) and urea (water-isocyanate) reactions, reducing cell collapse and enhancing structural density.
  • Applications: Automotive seat cushions, thermal insulation panels, high-resilience PU foams.

3. Flue Gas Treatment & CO2 Acid Gas Scrubbing

With global carbon neutrality ("dual-carbon") initiatives, sterically hindered morpholine amine derivatives serve as absorbent solvents for carbon capture and storage (CCS).

  • Key Benefits: High CO2 absorption capacity, low energy requirement for thermal solvent regeneration, low corrosivity toward steel equipment.
  • Applications: Natural gas sweetening, refinery gas desulfurization, industrial carbon capture systems.

4. Pharmaceutical Intermediates & Corrosion Inhibitors

Serves as a fundamental building block for APIs (active pharmaceutical ingredients), agrochemicals, and metal corrosion protection formulations.

  • Key Benefits: Strong surface adsorption film formation on ferrous metals; customizable precursor for active pharmaceutical molecules.
  • Applications: Boiler water treatment, cooling circuit corrosion inhibitors, custom synthesis APIs.

China Factory 4.0: Smart Manufacturing & Supply Chain Resilience

Headquartered in the Chemical Industry Park of Jinan City, Shandong Province, JIMPOCHEM’s manufacturing footprint spans over 500 acres. By deploying Industry 4.0 automation, DCS centralized digital control, and integrated environmental management, we guarantee supply reliability for multi-ton global orders.

16+
Years Industry Experience (Founded 2010)
500+
Acres Production Facility
200+
Countries & Regions Served
5000+
Global Corporate Clients

Automated DCS Smart Control

Real-time monitoring of pressure, temperature, catalytic dosage, and flow rates eliminates human error, guaranteeing batch-to-batch consistency with GC purity variance under 0.1%.

Full Supply Chain Integration

Direct strategic partnerships with top tier upstream petrochemical suppliers ensure continuous raw material availability, stabilizing costs during market volatility.

Green Chemistry & Carbon Reduction

Fully compliant wastewater, waste gas, and solid waste treatment plants supporting China's "Dual-Carbon" strategy, enabling our downstream clients to meet global ESG compliance requirements.

Global Procurement Guide: Packaging, Storage & Shipping

JIMPOCHEM provides tailored international logistics solutions, offering flexible packaging options, hazardous chemical transport documentation, and reliable global delivery capabilities.

Packaging Configurations

  • 200 kg Steel Drums: UN-approved heavy-duty steel drums, nitrogen flushed, 80 drums (16.0 MT) per 20' FCL.
  • 1000 kg IBC Tanks: Intermediate Bulk Containers for automated dispensing systems (20 MT per 20' FCL).
  • ISO Tank Containers: Bulk shipping options up to 22,000–24,000 kg for high-volume manufacturing operations.

Storage & Handling Guidelines

  • Storage Conditions: Store in a cool, dry, well-ventilated warehouse away from strong oxidizers, acids, and open flames.
  • Inert Gas Blanket: Nitrogen blanket recommended after opening to prevent moisture absorption and color degradation.
  • Shelf Life: 24 months from manufacturing date when stored unopened in original packaging.

Shipping Compliance & SDS

  • UN Number: UN 2735
  • Hazard Class: Class 8 (Corrosive Liquid)
  • Packing Group: PG II / PG III
  • Documentation: Full GHS 16-section SDS, COA, COO (Certificate of Origin), Commercial Invoice, and Packing List provided.

Regulatory Compliance, EHS & Global Technical Support

Meeting international chemical regulations is core to JIMPOCHEM’s operational philosophy. We provide thorough compliance documentation and technical support for seamless global integration.

E-E-A-T Compliance Framework

Our quality management team works closely with international regulatory agencies to maintain complete supply compliance:

  • EU REACH & UK REACH: Registration dossiers and tonnage coverage available for European Union and UK importers.
  • ISO Integrated Certifications: ISO 9001 (Quality Control System), ISO 14001 (Environmental System), and ISO 45001 (Occupational Health & Safety).
  • Full Traceability System: Digital batch codes linking raw material batch inputs, reactor logs, analytical testing reports, and shipping container numbers.

Customized Technical Services

We don't just supply products—we provide comprehensive chemical engineering assistance tailored to your processing setup:

  • Formulation Optimization: Dedicated R&D support for epoxy resin hardener formulations and polyurethane catalyst ratios.
  • Lab Sample Dispatch: Complimentary 500g analytical samples delivered via DHL/FedEx for lab testing and customer validation.
  • Custom Blending & Derivatives: Custom synthesis capabilities for modified amine hardeners and specialized morpholine derivatives.

About JIMPOCHEM CO., LTD – Designated Chemical Service Provider

JIMPOCHEM CO., LTD was established in 2010 and is headquartered in the Chemical Industry Park of Jinan City, Shandong Province. The company covers an area of over 500 acres and is a professional chemical raw material manufacturer that integrates research and development, production, sales, and technical services.

Our core focus is on high-end fine chemicals, cosmetic raw materials, and organic intermediates. We have obtained multiple product-related certifications, including ISO quality system certification and environmental management system certification, and are committed to providing high-quality chemical products and one-stop procurement service solutions to global customers.

Our core team comprises experts with over 16 years of experience in the chemical industry. This enables us not only to provide professional products but also to offer solutions in product development, formula optimization, and supply chain management. Exported to over 200 countries and regions across Europe, America, Southeast Asia, the Middle East, and Oceania, our products serve more than 5,000 international companies.

JIMPOCHEM Factory Overview

JIMPOCHEM Corporate Headquarters & R&D Hub (Jinan, Shandong)

Frequently Asked Questions (Technical & Procurement FAQ)

Find expert answers regarding 3-Morpholinopropylamine properties, custom synthesis, ordering procedures, and technical specifications.

What is the standard chemical purity of JIMPOCHEM’s 3-Morpholinopropylamine (CAS 123-00-2)?

Our industrial-grade product maintains a minimum purity of 99.0%, while our high-purity fine chemical grade achieves ≥ 99.5% by GC assay. Moisture content is tightly controlled below 0.10%, with a low Hazen color rating (≤20 APHA), making it suitable for sensitive epoxy systems and pharmaceutical intermediate synthesis.

How does 3-Morpholinopropylamine compare to other amine curing agents like DETA or TETA in epoxy formulations?

Compared to linear aliphatic polyamines like Diethylenetriamine (DETA) or Triethylenetetramine (TETA), 3-Morpholinopropylamine contains a tertiary morpholine ring. This provides a balance of catalytic acceleration, longer pot life at room temperature, reduced amine blush, improved moisture resistance, and enhanced thermal stability in cured epoxy networks.

What packaging options are available for international orders?

We offer standard 200 kg UN-approved steel drums (16.0 MT per 20ft container), 1,000 kg IBC tanks (20.0 MT per 20ft container), and ISO tank containers (up to 24 MT) for continuous industrial consumers. Customized drum branding and inert nitrogen blanketing are included.

Can JIMPOCHEM provide free samples for lab evaluation and quality verification?

Yes, we provide complimentary 250g to 500g testing samples alongside a Certificate of Analysis (COA) for qualified corporate clients. Express air courier shipping (DHL/FedEx) ensures fast global delivery.

What is the standard lead time for bulk orders from China?

Because we maintain an active manufacturing continuous line with 10,000 MT annual production capacity, standard drum orders ship within 7–10 working days after order confirmation. ISO tanks and custom contract orders generally dispatch within 14 days.

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